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How I do Drugs

03/10/2025

I do drugs, particularly estrogen. I am the kind of person who likes a set of structured steps to do important things like this. AS-level biology practicals truly terrorised me. So I figured I'd write a bunch of steps which I can follow for my injections. If anyone wants to contribute or add their own tips, that would be cool ^^

Hardware Required

  1. Estradiol vial
  2. Syringe (1mL)
  3. 2 syringe needles (recommended)
    • One 25G for drawing estrogen
    • One 26-29G for injections
  4. Alcohol wipes (2x)
    • Not baby wipes, they do not have alcohol
  5. Bandage

Steps

Read the additional context below before following these steps.

  1. Unwrap your syringe
  2. Use alcohol wipe to clean the membrane of the vial
  3. Insert syringe
  4. Draw up
    • If you see blood, you have pierced a vein. Remove the needle and apply cotton ball, disinfect, and bandage
  5. Draw up your volume of estradiol
  6. If you have a second (smaller) needle, swap to it
  7. Pinch the skin up where you want to inject
  8. Clean injection site with second alcohol wipe
  9. Stab yourself with syringe, at a 90' angle
  10. Push estrogen in, be patient
  11. After all estrogen has been injected, keep syringe inserted for an extra 30s
  12. Remove syringe
  13. Apply bandage if necessary

Additional Information

You can inject yourself in different areas. As I am more comfortable with sub-cutaneous injections, this reference is more for sub-q and not for intramuscular.

You can also inject yourself in different places. There are diagrams out there which show lumps of tissue you can inject into. For sub-q, a couple of the main places are the upper thigh and around the bellybutton. I find injecting into my stomach scary, so I guess I'm going with my leg instead.

For injection volumes, the source of my vial recommends "7 mg every 10 days" though you can also do "5mg every 7 days" so you have a fixed injection day. You should get blood tests to make sure testosterone is being properly suppressed. Emphasis on should - my brain can't seem to understand that this is important. Also, important note. Some syringes have a swappable needle. So you use the larger one to draw up, and the smaller one to inject. Not all syringes have this feature, and my insulin syringes do not. It's not the end of the world, but it's a nice-to-have.